Oslo Sports Trauma Research Center

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Information about project titled 'Focal cartilage defects in the knee and life quality'

Focal cartilage defects in the knee and life quality

Details about the project - category Details about the project - value
Project status: Published
Project manager: Stig Heir
Supervisor(s): Asbjørn Årøen, Lars Engebretsen
Coworker(s): Sverre Løken, Arne Ekeland, Tor K Nerhus


Patients with focal cartilage defects in the knee may suffer from both pain and functional impairment. Treatment options are often insufficient. It is not known, however, to what extent their complaints affect quality of life, compared with other knee disorders. Knee Injury and Osteoarthritis Outcome Score (KOOS) is a validated global knee score suitable for comparison of patients with knee complaints attributable to different causes.


Hypothesis: Complaints because of localized cartilage defects in the knee reduce quality of life measured by KOOS to a different extent than those due to anterior cruciate ligament deficiency and osteoarthritis, when comparing patients within the working population scheduled for surgery.


Methods: Previously registered KOOS baseline data on patients enrolled in different knee treatment studies were included in the present study; the patients were 18 to 67 years of age (working population) at data registration. The different patient categories were (1) patients with knee osteoarthritis enrolled for knee arthroplasty, (2) patients with knee osteoarthritis enrolled for osteotomies around the knee, (3) patients with focal cartilage lesions enrolled for cartilage repair, and (4) patients with anterior cruciate ligament–deficient knees enrolled for anterior cruciate ligament reconstruction. The KOOS subscale quality of life was  the main parameter for comparison of complaints.